GMP laboratory
for tried-and-tested pharmaceutical analytics

Physico-chem­ical analysis

Our services in the field of physico-chem­ical analysis include testing phar­ma­ceu­ti­cals for suspended solids, particle size and colour and deter­mining osmo­lality and fluid content.

Instru­mental analytics

  • Atomic absorp­tion spec­trom­etry (AAS) and atomic emis­sion spec­trom­etry (AES)

    using the following tech­niques: flame, nitrous oxide, graphite furnace, hydride and the corre­sponding diges­tion methods: acid diges­tion and microwave diges­tion to detect metals

  • Induc­tively coupled plasma mass spec­trom­etry (ICP-MS)

    for trace analysis of heavy metals such as mercury, lead or cadmium

  • Gas chro­matog­raphy (GC)

    with the following detec­tors: FID, NPD and MSD, e.g. deter­mi­na­tion of content and purity of phar­ma­ceu­tical raw mate­rials and finished prod­ucts, residual solvents, fatty acid composition

  • High-perfor­mance liquid chro­matog­raphy (HPLC)

    with the following detec­tors: UV/VIS, RI, ECD, fluo­res­cence, DAD, e.g. deter­mi­na­tion of content and purity of phar­ma­ceu­tical raw mate­rials and finished prod­ucts, biogenic amines and preservatives

  • Ion chro­matog­raphy (IC) with conduc­tivity detection

    for content deter­mi­na­tion of various anions and cations

  • UV-VIS spec­troscopy

    for qual­i­ta­tive and quan­ti­ta­tive deter­mi­na­tions; espe­cially enzymatics

  • IR absorp­tion spectroscopy

    for the spec­tral recording of liquid and solid substances

  • Thin-layer chro­matog­raphy (TLC)

    using a digital docu­men­ta­tion system for the purpose of qual­i­ta­tive deter­mi­na­tions and impu­rity testing

  • Deter­mi­na­tion of Total organic carbon (TOC)

    during purifi­ca­tion processes, for example

  • Amino acid analyzer

    For the detec­tion of ninhy­drin-posi­tive substances (amino acids) and their derivati­sa­tion prod­ucts as well as ammo­nium by UV detec­tion e.g. for the deter­mi­na­tion of iden­tity, purity and content

  • Capil­lary Elec­trophoresis (CE)

    Used for the deter­mi­na­tion of the chirality of small mole­cules, Capil­lary Isoelec­tric Focusing (CIEF) or Capil­lary Gel Elec­trophoresis. For the deter­mi­na­tion of the purity, iden­tity, and content of proteins (e.g. mono­clonal antibodies)

pharma&med pharma methoden entwicklung Labor
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